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Impact of downstream effects of glucocorticoid receptor dysfunction on organ function in critical illness-associated systemic inflammation
Glucocorticoids (GCs) are stress hormones that regulate developmental and physiological processes and are among the most potent anti-inflammatory drugs to suppress chronic and acute inflammation. GCs act through the glucocorticoid receptor (GR), a ubiquitously expressed ligand-activated transcriptio...
Autores principales: | Wepler, Martin, Preuss, Jonathan M., Merz, Tamara, McCook, Oscar, Radermacher, Peter, Tuckermann, Jan P., Vettorazzi, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746781/ https://www.ncbi.nlm.nih.gov/pubmed/33336296 http://dx.doi.org/10.1186/s40635-020-00325-z |
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