Cargando…
Complications and Pathophysiology of COVID-19 in the Nervous System
The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746805/ https://www.ncbi.nlm.nih.gov/pubmed/33343486 http://dx.doi.org/10.3389/fneur.2020.573421 |
_version_ | 1783624867755589632 |
---|---|
author | Yu, Haiyang Sun, Tong Feng, Juan |
author_facet | Yu, Haiyang Sun, Tong Feng, Juan |
author_sort | Yu, Haiyang |
collection | PubMed |
description | The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory distress syndrome. In addition to respiratory symptoms, neurological damage also occurs in some patients. However, the mechanisms by which SARS-CoV-2 invades the nervous system have not been elucidated yet. In order to provide some reference for designing optimal therapeutic strategies, we have discussed the complications and potential mechanisms of COVID-19 in the nervous system in this review. |
format | Online Article Text |
id | pubmed-7746805 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77468052020-12-19 Complications and Pathophysiology of COVID-19 in the Nervous System Yu, Haiyang Sun, Tong Feng, Juan Front Neurol Neurology The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory distress syndrome. In addition to respiratory symptoms, neurological damage also occurs in some patients. However, the mechanisms by which SARS-CoV-2 invades the nervous system have not been elucidated yet. In order to provide some reference for designing optimal therapeutic strategies, we have discussed the complications and potential mechanisms of COVID-19 in the nervous system in this review. Frontiers Media S.A. 2020-12-04 /pmc/articles/PMC7746805/ /pubmed/33343486 http://dx.doi.org/10.3389/fneur.2020.573421 Text en Copyright © 2020 Yu, Sun and Feng. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Yu, Haiyang Sun, Tong Feng, Juan Complications and Pathophysiology of COVID-19 in the Nervous System |
title | Complications and Pathophysiology of COVID-19 in the Nervous System |
title_full | Complications and Pathophysiology of COVID-19 in the Nervous System |
title_fullStr | Complications and Pathophysiology of COVID-19 in the Nervous System |
title_full_unstemmed | Complications and Pathophysiology of COVID-19 in the Nervous System |
title_short | Complications and Pathophysiology of COVID-19 in the Nervous System |
title_sort | complications and pathophysiology of covid-19 in the nervous system |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746805/ https://www.ncbi.nlm.nih.gov/pubmed/33343486 http://dx.doi.org/10.3389/fneur.2020.573421 |
work_keys_str_mv | AT yuhaiyang complicationsandpathophysiologyofcovid19inthenervoussystem AT suntong complicationsandpathophysiologyofcovid19inthenervoussystem AT fengjuan complicationsandpathophysiologyofcovid19inthenervoussystem |