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Complications and Pathophysiology of COVID-19 in the Nervous System

The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory...

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Autores principales: Yu, Haiyang, Sun, Tong, Feng, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746805/
https://www.ncbi.nlm.nih.gov/pubmed/33343486
http://dx.doi.org/10.3389/fneur.2020.573421
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author Yu, Haiyang
Sun, Tong
Feng, Juan
author_facet Yu, Haiyang
Sun, Tong
Feng, Juan
author_sort Yu, Haiyang
collection PubMed
description The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory distress syndrome. In addition to respiratory symptoms, neurological damage also occurs in some patients. However, the mechanisms by which SARS-CoV-2 invades the nervous system have not been elucidated yet. In order to provide some reference for designing optimal therapeutic strategies, we have discussed the complications and potential mechanisms of COVID-19 in the nervous system in this review.
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spelling pubmed-77468052020-12-19 Complications and Pathophysiology of COVID-19 in the Nervous System Yu, Haiyang Sun, Tong Feng, Juan Front Neurol Neurology The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global public health threat. Majority of the patients with COVID-19 have fever, cough, and fatigue. Critically ill patients can develop dyspnea and acute respiratory distress syndrome. In addition to respiratory symptoms, neurological damage also occurs in some patients. However, the mechanisms by which SARS-CoV-2 invades the nervous system have not been elucidated yet. In order to provide some reference for designing optimal therapeutic strategies, we have discussed the complications and potential mechanisms of COVID-19 in the nervous system in this review. Frontiers Media S.A. 2020-12-04 /pmc/articles/PMC7746805/ /pubmed/33343486 http://dx.doi.org/10.3389/fneur.2020.573421 Text en Copyright © 2020 Yu, Sun and Feng. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Yu, Haiyang
Sun, Tong
Feng, Juan
Complications and Pathophysiology of COVID-19 in the Nervous System
title Complications and Pathophysiology of COVID-19 in the Nervous System
title_full Complications and Pathophysiology of COVID-19 in the Nervous System
title_fullStr Complications and Pathophysiology of COVID-19 in the Nervous System
title_full_unstemmed Complications and Pathophysiology of COVID-19 in the Nervous System
title_short Complications and Pathophysiology of COVID-19 in the Nervous System
title_sort complications and pathophysiology of covid-19 in the nervous system
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746805/
https://www.ncbi.nlm.nih.gov/pubmed/33343486
http://dx.doi.org/10.3389/fneur.2020.573421
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