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Multiple Rare Risk Coding Variants in Postsynaptic Density-Related Genes Associated With Schizophrenia Susceptibility

OBJECTIVE: Schizophrenia is a chronic debilitating neurobiological disorder of aberrant synaptic connectivity and synaptogenesis. Postsynaptic density (PSD)–related proteins in N-methyl-D-aspartate receptor–postsynaptic signaling complexes are crucial to regulating the synaptic transmission and func...

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Detalles Bibliográficos
Autores principales: Hu, Tsung-Ming, Wang, Ying-Chieh, Wu, Chia-Liang, Hsu, Shih-Hsin, Tsai, Hsin-Yao, Cheng, Min-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746813/
https://www.ncbi.nlm.nih.gov/pubmed/33343614
http://dx.doi.org/10.3389/fgene.2020.524258