Cargando…

Dasatinib Inhibits Lung Cancer Cell Growth and Patient Derived Tumor Growth in Mice by Targeting LIMK1

Lung cancer is a leading cause cancer-related death with diversity. A promising approach to meet the need for improved cancer treatment is drug repurposing. Dasatinib, a second generation of tyrosine kinase inhibitors (TKIs), is a potent treatment agent for chronic myeloid leukemia (CML) approved by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Man, Tian, Jie, Wang, Rui, Song, Mengqiu, Zhao, Ran, Chen, Hanyong, Liu, Kangdong, Shim, Jung-Hyun, Zhu, Feng, Dong, Zigang, Lee, Mee-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746816/ https://www.ncbi.nlm.nih.gov/pubmed/33344441 http://dx.doi.org/10.3389/fcell.2020.556532

Ejemplares similares

Targeting LIMK1 with luteolin inhibits the growth of lung cancer in vitro and in vivo
por: Zhang, Man, et al.
Publicado: (2021)

Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivo
por: Yin, Shuying, et al.
Publicado: (2020)

3-Deoxysappanchalcone Inhibits Skin Cancer Proliferation by Regulating T-Lymphokine-Activated Killer Cell-Originated Protein Kinase in vitro and in vivo
por: Fu, Xiaorong, et al.
Publicado: (2021)

Honokiol Inhibits Melanoma Growth by Targeting Keratin 18 in vitro and in vivo
por: Liu, Tingting, et al.
Publicado: (2020)

The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading?
por: Liu, Hui, et al.
Publicado: (2021)

(S)-10-Hydroxycamptothecin Inhibits Esophageal Squamous Cell Carcinoma Growth In Vitro and In Vivo Via Decreasing Topoisomerase I Enzyme Activity
por: Song, Mengqiu, et al.
Publicado: (2019)

The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse
por: Bolger-Munro, Madison, et al.
Publicado: (2021)

Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo
por: Liu, Xuejiao, et al.
Publicado: (2019)

Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo
por: Yin, Fanxiang, et al.
Publicado: (2022)

Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells
por: Hegedüs, Luca, et al.
Publicado: (2022)

LIMK1/2 inhibitor LIMKi 3 suppresses porcine oocyte maturation
por: Jia, Ru-Xia, et al.
Publicado: (2016)

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2
por: Wang, Li, et al.
Publicado: (2018)

Acetylshikonin suppressed growth of colorectal tumour tissue and cells by inhibiting the intracellular kinase, T‐lymphokine‐activated killer cell‐originated protein kinase.
por: Zhao, Ran, et al.
Publicado: (2020)

The Effect of Mechanical Stretch on Myotube Growth Suppression by Colon-26 Tumor-Derived Factors
por: Halle, Jessica L., et al.
Publicado: (2021)

A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo
por: Shin, Seung Ho, et al.
Publicado: (2017)

Growth and Osteogenic Differentiation of Discarded Gingiva-Derived Mesenchymal Stem Cells on a Commercial Scaffold
por: Cristaldi, Marta, et al.
Publicado: (2020)

Platelet-Derived Growth Factor-D Activates Complement System to Propagate Macrophage Polarization and Neovascularization
por: Xiong, Zhen, et al.
Publicado: (2021)

Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics
por: Gangadaran, Prakash, et al.
Publicado: (2022)

Cardiac Fibroblast Growth Factor 23 Excess Does Not Induce Left Ventricular Hypertrophy in Healthy Mice
por: Leifheit-Nestler, Maren, et al.
Publicado: (2021)

Corrigendum: Platelet-Derived Growth Factor-D Activates Complement System to Propagate Macrophage Polarization and Neovascularization
por: Xiong, Zhen, et al.
Publicado: (2022)

Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids
por: Cheaito, Katia, et al.
Publicado: (2020)

Self-assembled adipose-derived mesenchymal stem cells as an extracellular matrix component- and growth factor-enriched filler
por: Park, Choa, et al.
Publicado: (2023)

Neural Epidermal Growth Factor-Like Like Protein 2 Is Expressed in Human Oligodendroglial Cell Types
por: Shaker, Mohammed R., et al.
Publicado: (2022)

Growth Hormone/Insulin Growth Factor Axis in Sex Steroid Associated Disorders and Related Cancers
por: Bleach, Rachel, et al.
Publicado: (2021)

G-Protein-Coupled Estrogen Receptor-1 Positively Regulates the Growth Plate Chondrocyte Proliferation in Female Pubertal Mice
por: Chou, Ya-Shuan, et al.
Publicado: (2021)

Immature Follicular Origins and Disrupted Oocyte Growth Pathways Contribute to Decreased Gamete Quality During Reproductive Juvenescence in Mice
por: Kusuhara, Atsuko, et al.
Publicado: (2021)

Suppressor of fused-restrained Hedgehog signaling in chondrocytes is critical for epiphyseal growth plate maintenance and limb elongation in juvenile mice
por: Xiu, Chunmei, et al.
Publicado: (2022)

Transforming Growth Factor-β Signaling Regulates Tooth Root Dentinogenesis by Cooperation With Wnt Signaling
por: Zhang, Ran, et al.
Publicado: (2021)

Quo Vadis Cell Growth and Division?
por: Kaldis, Philipp
Publicado: (2016)

Zebrafish as a Model for Germ Cell Regeneration
por: Cao, Zigang, et al.
Publicado: (2021)

Label-Free Infrared Spectral Histology of Skin Tissue Part II: Impact of a Lumican-Derived Peptide on Melanoma Growth
por: Brézillon, Stéphane, et al.
Publicado: (2020)

AIM2 Inhibits BRAF-Mutant Colorectal Cancer Growth in a Caspase-1-Dependent Manner
por: Shah, Shailendra, et al.
Publicado: (2021)

Treatment of growth hormone attenuates hepatic steatosis in hyperlipidemic mice via downregulation of hepatic CD36 expression
por: Jang, Hyung Seok, et al.
Publicado: (2020)

Editorial: Craniofacial Growth and Development: Novel Insights
por: Küchler, Erika Calvano, et al.
Publicado: (2021)

The Role of Syncytin in Placental Angiogenesis and Fetal Growth
por: Wang, Ya-Nan, et al.
Publicado: (2022)

Regulation of Myostatin on the Growth and Development of Skeletal Muscle
por: Chen, Ming-Ming, et al.
Publicado: (2021)

The regulation of adipocyte growth in white adipose tissue
por: Li, Qian, et al.
Publicado: (2022)

Editorial: Protein homeostasis in growth, development and disease
por: Masciarelli, Silvia, et al.
Publicado: (2023)

Editorial: Growth and Tissue Regeneration with focus on Proteoglycans
por: Pedersen, Mona Elisabeth, et al.
Publicado: (2023)

Galectin-3 Enhances Vascular Endothelial Growth Factor-A Receptor 2 Activity in the Presence of Vascular Endothelial Growth Factor
por: Cano, Issahy, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7c0iht9dukf1bema8ckp97qa0f