Molecular Dynamics Simulation of T10609C and C10676G Mutations of Mitochondrial ND4L Gene Associated With Proton Translocation in Type 2 Diabetes Mellitus and Cataract Patients

The mutation rate of mitochondrial DNA (mtDNA) is 17 times higher than nuclear DNA, and these mutations can cause mitochondrial disease in 1 of 10.000 people. The T10609C mutation was identified in type 2 diabetes mellitus (T2DM) patients and the C10676G mutation in cataract patients, with both muta...

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Detalles Bibliográficos
Autores principales: Destiarani, Wanda, Mulyani, Rahmaniar, Yusuf, Muhammad, Maksum, Iman Permana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747115/
https://www.ncbi.nlm.nih.gov/pubmed/33402819
http://dx.doi.org/10.1177/1177932220978672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747115/
https://www.ncbi.nlm.nih.gov/pubmed/33402819
http://dx.doi.org/10.1177/1177932220978672

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