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Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine

[Image: see text] Radiotherapy and immunotherapy are two key treatments for cancer. There is growing evidence that they are also synergistic, and combination treatments are being studied extensively in the clinical setting. In addition, there is emerging evidence that nanotechnology-enabled therapeu...

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Autores principales: Hagan, C. Tilden, Mi, Yu, Knape, Nicole M., Wang, Andrew Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747221/
https://www.ncbi.nlm.nih.gov/pubmed/33251789
http://dx.doi.org/10.1021/acs.bioconjchem.0c00520
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author Hagan, C. Tilden
Mi, Yu
Knape, Nicole M.
Wang, Andrew Z.
author_facet Hagan, C. Tilden
Mi, Yu
Knape, Nicole M.
Wang, Andrew Z.
author_sort Hagan, C. Tilden
collection PubMed
description [Image: see text] Radiotherapy and immunotherapy are two key treatments for cancer. There is growing evidence that they are also synergistic, and combination treatments are being studied extensively in the clinical setting. In addition, there is emerging evidence that nanotechnology-enabled therapeutics can potentiate both radiotherapy and immunotherapy, in turn improving both treatments. This is an exciting new area of interdisciplinary science and has significant potential for major clinical impact. Some of the approaches in this area have already reached the clinical stage. In this review, we will discuss recent advances in the interface between radiotherapy, immunotherapy, and nanomedicine. We plan to review the many approaches to combine these three fields for cancer treatment.
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spelling pubmed-77472212020-12-18 Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine Hagan, C. Tilden Mi, Yu Knape, Nicole M. Wang, Andrew Z. Bioconjug Chem [Image: see text] Radiotherapy and immunotherapy are two key treatments for cancer. There is growing evidence that they are also synergistic, and combination treatments are being studied extensively in the clinical setting. In addition, there is emerging evidence that nanotechnology-enabled therapeutics can potentiate both radiotherapy and immunotherapy, in turn improving both treatments. This is an exciting new area of interdisciplinary science and has significant potential for major clinical impact. Some of the approaches in this area have already reached the clinical stage. In this review, we will discuss recent advances in the interface between radiotherapy, immunotherapy, and nanomedicine. We plan to review the many approaches to combine these three fields for cancer treatment. American Chemical Society 2020-11-30 2020-12-16 /pmc/articles/PMC7747221/ /pubmed/33251789 http://dx.doi.org/10.1021/acs.bioconjchem.0c00520 Text en © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Hagan, C. Tilden
Mi, Yu
Knape, Nicole M.
Wang, Andrew Z.
Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine
title Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine
title_full Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine
title_fullStr Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine
title_full_unstemmed Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine
title_short Enhancing Combined Immunotherapy and Radiotherapy through Nanomedicine
title_sort enhancing combined immunotherapy and radiotherapy through nanomedicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747221/
https://www.ncbi.nlm.nih.gov/pubmed/33251789
http://dx.doi.org/10.1021/acs.bioconjchem.0c00520
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