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pH-controlled stacking direction of the β-strands in peptide fibrils
Peptides provide a framework for generating functional biopolymers. In this study, the pH-dependent structural changes in the 21–29 fragment peptide of β(2)-microglobulin (β(2)m(21–29)) during self-aggregation, i.e., the formation of an amyloid fibril, were discussed. The β-sheet structures formed d...
Autores principales: | Tseng, Wei-Hsuan, Chen, Szu-Hua, Hiramatsu, Hirotsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747703/ https://www.ncbi.nlm.nih.gov/pubmed/33335192 http://dx.doi.org/10.1038/s41598-020-79001-x |
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