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Herpes simplex virus 1 targets IRF7 via ICP0 to limit type I IFN induction

Herpes simplex keratitis (HSK), caused by herpes simplex virus type 1 (HSV-1) infection, is the commonest cause of infectious blindness in the developed world. Following infection the virus is initially suspended in the tear film, where it encounters a multi-pronged immune response comprising enzyme...

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Detalles Bibliográficos
Autores principales:	Shahnazaryan, David, Khalil, Rana, Wynne, Claire, Jefferies, Caroline A., Ní Gabhann-Dromgoole, Joan, Murphy, Conor C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747705/ https://www.ncbi.nlm.nih.gov/pubmed/33335135 http://dx.doi.org/10.1038/s41598-020-77725-4

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