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DNA damage in human glomerular endothelial cells induces nodular glomerulosclerosis via an ATR and ANXA2 pathway
Collagen type VI (COL6) deposition occurs in various glomerular diseases, causing serious pathological damage like nodular lesions. However, the mechanisms underlying the deposition of COL6 remain unclear. In renal biopsy samples, immunohistochemical analyses revealed that COL6 and phosphorylated hi...
Autores principales: | Fujii, Ai, Sunatani, Yumi, Furuichi, Kengo, Fujimoto, Keiji, Adachi, Hiroki, Iwabuchi, Kuniyoshi, Yokoyama, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747722/ https://www.ncbi.nlm.nih.gov/pubmed/33335142 http://dx.doi.org/10.1038/s41598-020-79106-3 |
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