Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid

Chagas Disease is caused by Trypanosoma cruzi. This infection is endemic in the Americas region. Neurological Chagas reactivation is diagnosed through the visualization of the parasite in the cerebrospinal fluid, blood, or tissue samples. Herein, we report the visualization of trypomastigotes by dir...

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Detalles Bibliográficos
Autores principales: Lopez-Albizu, Constanza, Bravo, Martín Pablo, Pico, Marisa, Fernandez, Marisa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747806/
https://www.ncbi.nlm.nih.gov/pubmed/33338120
http://dx.doi.org/10.1590/0037-8682-0326-2020
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author Lopez-Albizu, Constanza
Bravo, Martín Pablo
Pico, Marisa
Fernandez, Marisa L.
author_facet Lopez-Albizu, Constanza
Bravo, Martín Pablo
Pico, Marisa
Fernandez, Marisa L.
author_sort Lopez-Albizu, Constanza
collection PubMed
description Chagas Disease is caused by Trypanosoma cruzi. This infection is endemic in the Americas region. Neurological Chagas reactivation is diagnosed through the visualization of the parasite in the cerebrospinal fluid, blood, or tissue samples. Herein, we report the visualization of trypomastigotes by direct microscopic observation of a brain biopsy specimen and its preservation fluid (PF) in a paitient infected with VIH and T. cruzi. This easy and simple diagnostic method coupled with quantitative polymerase chain reaction can be used in all tissue biopsies and PF of T. cruzi seropositive patients, suspected of Chagas disease reactivation.
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spelling pubmed-77478062020-12-22 Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid Lopez-Albizu, Constanza Bravo, Martín Pablo Pico, Marisa Fernandez, Marisa L. Rev Soc Bras Med Trop Case Report Chagas Disease is caused by Trypanosoma cruzi. This infection is endemic in the Americas region. Neurological Chagas reactivation is diagnosed through the visualization of the parasite in the cerebrospinal fluid, blood, or tissue samples. Herein, we report the visualization of trypomastigotes by direct microscopic observation of a brain biopsy specimen and its preservation fluid (PF) in a paitient infected with VIH and T. cruzi. This easy and simple diagnostic method coupled with quantitative polymerase chain reaction can be used in all tissue biopsies and PF of T. cruzi seropositive patients, suspected of Chagas disease reactivation. Sociedade Brasileira de Medicina Tropical - SBMT 2020-12-21 /pmc/articles/PMC7747806/ /pubmed/33338120 http://dx.doi.org/10.1590/0037-8682-0326-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Case Report
Lopez-Albizu, Constanza
Bravo, Martín Pablo
Pico, Marisa
Fernandez, Marisa L.
Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid
title Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid
title_full Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid
title_fullStr Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid
title_full_unstemmed Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid
title_short Case report of Chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid
title_sort case report of chagas disease reactivation: new diagnosis tool by direct microscopic observation of biopsy specimen and its preservation fluid
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747806/
https://www.ncbi.nlm.nih.gov/pubmed/33338120
http://dx.doi.org/10.1590/0037-8682-0326-2020
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