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Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis

Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with miltefos...

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Detalles Bibliográficos
Autores principales: Pandey, Krishna, Pal, Biplab, Topno, Roshan Kamal, Lal, Chandra Shekhar, Das, Vidya Nand Rabi, Das, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747827/
https://www.ncbi.nlm.nih.gov/pubmed/33338118
http://dx.doi.org/10.1590/0037-8682-0208-2020
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author Pandey, Krishna
Pal, Biplab
Topno, Roshan Kamal
Lal, Chandra Shekhar
Das, Vidya Nand Rabi
Das, Pradeep
author_facet Pandey, Krishna
Pal, Biplab
Topno, Roshan Kamal
Lal, Chandra Shekhar
Das, Vidya Nand Rabi
Das, Pradeep
author_sort Pandey, Krishna
collection PubMed
description Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with miltefosine for post-kala-azar dermal leishmaniasis. This adverse effect developed after 15 days of miltefosine consumption, and the patient himself discontinued the treatment. The ophthalmic complication was completely resolved with antibiotics and steroid eye drops. After recovery from the ophthalmic complication, the patient was successfully treated with liposomal amphotericin B for the skin lesions.
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spelling pubmed-77478272020-12-22 Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis Pandey, Krishna Pal, Biplab Topno, Roshan Kamal Lal, Chandra Shekhar Das, Vidya Nand Rabi Das, Pradeep Rev Soc Bras Med Trop Case Report Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with miltefosine for post-kala-azar dermal leishmaniasis. This adverse effect developed after 15 days of miltefosine consumption, and the patient himself discontinued the treatment. The ophthalmic complication was completely resolved with antibiotics and steroid eye drops. After recovery from the ophthalmic complication, the patient was successfully treated with liposomal amphotericin B for the skin lesions. Sociedade Brasileira de Medicina Tropical - SBMT 2020-12-21 /pmc/articles/PMC7747827/ /pubmed/33338118 http://dx.doi.org/10.1590/0037-8682-0208-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Case Report
Pandey, Krishna
Pal, Biplab
Topno, Roshan Kamal
Lal, Chandra Shekhar
Das, Vidya Nand Rabi
Das, Pradeep
Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
title Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
title_full Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
title_fullStr Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
title_full_unstemmed Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
title_short Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
title_sort acute uveitis: a rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747827/
https://www.ncbi.nlm.nih.gov/pubmed/33338118
http://dx.doi.org/10.1590/0037-8682-0208-2020
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