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Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis
Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with miltefos...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Medicina Tropical - SBMT
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747827/ https://www.ncbi.nlm.nih.gov/pubmed/33338118 http://dx.doi.org/10.1590/0037-8682-0208-2020 |
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author | Pandey, Krishna Pal, Biplab Topno, Roshan Kamal Lal, Chandra Shekhar Das, Vidya Nand Rabi Das, Pradeep |
author_facet | Pandey, Krishna Pal, Biplab Topno, Roshan Kamal Lal, Chandra Shekhar Das, Vidya Nand Rabi Das, Pradeep |
author_sort | Pandey, Krishna |
collection | PubMed |
description | Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with miltefosine for post-kala-azar dermal leishmaniasis. This adverse effect developed after 15 days of miltefosine consumption, and the patient himself discontinued the treatment. The ophthalmic complication was completely resolved with antibiotics and steroid eye drops. After recovery from the ophthalmic complication, the patient was successfully treated with liposomal amphotericin B for the skin lesions. |
format | Online Article Text |
id | pubmed-7747827 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Sociedade Brasileira de Medicina Tropical - SBMT |
record_format | MEDLINE/PubMed |
spelling | pubmed-77478272020-12-22 Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis Pandey, Krishna Pal, Biplab Topno, Roshan Kamal Lal, Chandra Shekhar Das, Vidya Nand Rabi Das, Pradeep Rev Soc Bras Med Trop Case Report Post-kala-azar dermal leishmaniasis is a skin disorder occurring in 5-10% of visceral leishmaniasis patients after treatment with miltefosine,the first-line drug for this skin disorder. We reported a case of acute anterior uveitis,a rare adverse effect, experienced by a patient treated with miltefosine for post-kala-azar dermal leishmaniasis. This adverse effect developed after 15 days of miltefosine consumption, and the patient himself discontinued the treatment. The ophthalmic complication was completely resolved with antibiotics and steroid eye drops. After recovery from the ophthalmic complication, the patient was successfully treated with liposomal amphotericin B for the skin lesions. Sociedade Brasileira de Medicina Tropical - SBMT 2020-12-21 /pmc/articles/PMC7747827/ /pubmed/33338118 http://dx.doi.org/10.1590/0037-8682-0208-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License |
spellingShingle | Case Report Pandey, Krishna Pal, Biplab Topno, Roshan Kamal Lal, Chandra Shekhar Das, Vidya Nand Rabi Das, Pradeep Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis |
title | Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis |
title_full | Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis |
title_fullStr | Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis |
title_full_unstemmed | Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis |
title_short | Acute uveitis: A rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis |
title_sort | acute uveitis: a rare adverse effect of miltefosine in the treatment of post-kala-azar dermal leishmaniasis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747827/ https://www.ncbi.nlm.nih.gov/pubmed/33338118 http://dx.doi.org/10.1590/0037-8682-0208-2020 |
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