Immune-stimulatory (TK/Flt3L) gene therapy opens the door to a promising new treatment strategy against brainstem gliomas

Diffuse intrinsic pontine glioma (DIPG) is a rare brainstem tumor which carries a dismal prognosis. To date. there are no effective treatments for DIPG. Transcriptomic studies have shown that DIPGs have a distinct profile compared to hemispheric high-grade pediatric gliomas. These specific genomic f...

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Detalles Bibliográficos
Autores principales: Faisal, Syed M., Mendez, Flor M., Nunez, Fernando, Castro, Maria G., Lowenstein, Pedro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747859/
https://www.ncbi.nlm.nih.gov/pubmed/33400737
http://dx.doi.org/10.18632/oncotarget.27834

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