Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model

In the present investigation, we synthesized chalcone bearing naphthalene compound d1, and on the basis of (1)H-NMR, (13)C NMR, and LC-MS data we had specified the structure of the synthesized compound. The resultant compound d1 was assessed for their antiproliferative action against human cancer ce...

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Detalles Bibliográficos
Autores principales: Guruswamy, Dileep Kumar M., Balaji, Kyathegowdana Doddi Srivinavasa, Dharmappa, Kattepura Krishnappa, Jayarama, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747862/
https://www.ncbi.nlm.nih.gov/pubmed/33400732
http://dx.doi.org/10.18632/oncotarget.27836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747862/
https://www.ncbi.nlm.nih.gov/pubmed/33400732
http://dx.doi.org/10.18632/oncotarget.27836

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