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Identification of nuclear export signal in KLLN suggests potential role in proteasomal degradation in cancer cells
Germline and somatic promoter hypermethylation of KLLN has been found in diverse heritable and sporadic cancers, respectively. KLLN has many identified tumor suppressor functions, and when first reported, was thought to be exclusively nuclear. Here, we report on KLLN localization in both the nucleus...
Autores principales: | Sankunny, Madhav, Eng, Charis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747863/ https://www.ncbi.nlm.nih.gov/pubmed/33400740 http://dx.doi.org/10.18632/oncotarget.27833 |
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