Rapid and long-lasting antidepressant-like effects of ketamine and their relationship with the expression of brain enzymes, BDNF, and astrocytes

Ketamine (KET) is an N-methyl-D-aspartate (NMDA) antagonist with rapid and long-lasting antidepressant effects, but how the drug shows its sustained effects is still a matter of controversy. The objectives were to evaluate the mechanisms for KET rapid (30 min) and long-lasting (15 and 30 days after)...

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Detalles Bibliográficos
Autores principales: Viana, G.S.B., do Vale, E.M., de Araujo, A.R.A., Coelho, N.C., Andrade, S.M., da Costa, R.O., de Aquino, P.E.A., de Sousa, C.N.S., de Medeiros, I.S., de Vasconcelos, S.M.M., Neves, K.R.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747878/
https://www.ncbi.nlm.nih.gov/pubmed/33331415
http://dx.doi.org/10.1590/1414-431X202010107

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