Cargando…

Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy in adults and accounts for 85–90% of all primary liver cancer. Based on the estimation by the International Agency for Research on Cancer in 2018, liver cancer is the fourth leading cause of cancer death globally. Dihydroarte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Tzu-En, Deng, Yi-Ning, Hsu, Jui-Ling, Leu, Wohn-Jenn, Marchesi, Elena, Capobianco, Massimo L., Marchetti, Paolo, Navacchia, Maria Luisa, Guh, Jih-Hwa, Perrone, Daniela, Hsu, Lih-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748086/ https://www.ncbi.nlm.nih.gov/pubmed/33343369 http://dx.doi.org/10.3389/fphar.2020.599067

Ejemplares similares

Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells
por: Hsu, Ya-Fen, et al.
Publicado: (2023)

Dihydroartemisinin-Ursodeoxycholic Bile Acid Hybrids in the Fight against SARS-CoV-2
por: Marchesi, Elena, et al.
Publicado: (2023)

Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer
por: Hsu, Jui-Ling, et al.
Publicado: (2021)

Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer – a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation
por: Chang, Wei-Ling, et al.
Publicado: (2015)

Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and -Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents
por: Hsu, Jui-Ling, et al.
Publicado: (2018)

Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling
por: Hsu, Jui-Ling, et al.
Publicado: (2020)

Reevesioside A, a Cardenolide Glycoside, Induces Anticancer Activity against Human Hormone-Refractory Prostate Cancers through Suppression of c-myc Expression and Induction of G1 Arrest of the Cell Cycle
por: Leu, Wohn-Jenn, et al.
Publicado: (2014)

Extract From Plectranthus amboinicus Inhibit Maturation and Release of Interleukin 1β Through Inhibition of NF-κB Nuclear Translocation and NLRP3 Inflammasome Activation
por: Leu, Wohn-Jenn, et al.
Publicado: (2019)

The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis
por: Sheng, Yi-Hua, et al.
Publicado: (2020)

Bile Acid Conjugates with Anticancer Activity: Most Recent Research
por: Navacchia, Maria Luisa, et al.
Publicado: (2020)

The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling Pathways
por: Weng, Hao-Cheng, et al.
Publicado: (2022)

Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps—Structure-Activity-Relationship and Mechanism Studies
por: Leu, Wohn-Jenn, et al.
Publicado: (2020)

Dihydroartemisinin: A Potential Natural Anticancer Drug
por: Dai, Xiaoshuo, et al.
Publicado: (2021)

Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells—Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy
por: Chan, She-Hung, et al.
Publicado: (2020)

Resistance to Dihydroartemisinin
por: Cojean, Sandrine, et al.
Publicado: (2006)

Resistance to Dihydroartemisinin
por: Legrand, Eric, et al.
Publicado: (2007)

Rational Design of Nucleoside–Bile Acid Conjugates Incorporating a Triazole Moiety for Anticancer Evaluation and SAR Exploration
por: Navacchia, Maria Luisa, et al.
Publicado: (2017)

Mechanisms of Dihydroartemisinin and Dihydroartemisinin/Holotransferrin Cytotoxicity in T-Cell Lymphoma Cells
por: Wang, Qiuyan, et al.
Publicado: (2015)

Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways
por: Chan, Mei-Ling, et al.
Publicado: (2017)

Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death against Human Non-Small Cell Lung Cancers
por: Chang, Ya-Ching, et al.
Publicado: (2020)

Zinc Protoporphyrin-9 Potentiates the Anticancer Activity of Dihydroartemisinin
por: Zhang, Yu, et al.
Publicado: (2023)

Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways
por: Leu, Wohn-Jenn, et al.
Publicado: (2016)

Anticancer Effects of Dihydroartemisinin on Human Esophageal Cancer Cells In Vivo
por: Jiang, Cailing, et al.
Publicado: (2018)

Epi-reevesioside F inhibits Na(+)/K(+)-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma
por: Hsu, Jui-Ling, et al.
Publicado: (2015)

Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems
por: Chang, Jo-Fan, et al.
Publicado: (2019)

The pharmaceutical death-ride of dihydroartemisinin
por: Jansen, Frans Herwig
Publicado: (2010)

Pilot study: bioequivalence of dihydroartemisinin in dihydroartemisinin-piperaquine tablet generic formulation in healthy Indonesian volunteers
por: Isnawati, Ani, et al.
Publicado: (2023)

Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect
por: Leu, Wohn-Jenn, et al.
Publicado: (2021)

Molecular Hybridization as a Strategy for Developing Artemisinin-Derived Anticancer Candidates
por: Marchesi, Elena, et al.
Publicado: (2023)

Effects of dihydroartemisinin on the gut microbiome of mice
por: Liu, Yanyan, et al.
Publicado: (2020)

Three-Carbon Linked Dihydroartemisinin-Isatin Hybrids: Design, Synthesis and Their Antiproliferative Anticancer Activity
por: Dong, Min, et al.
Publicado: (2022)

Redetermination of dihydroartemisinin at 103 (2) K
por: Jasinski, Jerry P., et al.
Publicado: (2007)

Stereodynamic Investigation of Labile Stereogenic Centres in Dihydroartemisinin
por: D’Acquarica, Ilaria, et al.
Publicado: (2010)

Therapeutic effects of dihydroartemisinin and transferrin against glioblastoma
por: Kim, Suk Hee, et al.
Publicado: (2016)

Dihydroartemisinin as a Sensitizing Agent in Cancer Therapies
por: Li, Qingrong, et al.
Publicado: (2021)

Artesunate and Dihydroartemisinin Inhibit Rabies Virus Replication
por: Luo, Jun, et al.
Publicado: (2021)

Discovery of New Glucose Uptake Inhibitors as Potential Anticancer Agents by Non-Radioactive Cell-Based Assays
por: Hung, Hsueh-Chih, et al.
Publicado: (2022)

Dihydroartemisinin‐piperaquine for treating uncomplicated Plasmodium falciparum malaria
por: Zani, Babalwa, et al.
Publicado: (2014)

Probucol dramatically enhances dihydroartemisinin effect in murine malaria
por: Kume, Aiko, et al.
Publicado: (2016)

Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancer
por: Zhang, Fei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9p28b988rnasmiugl2ciuep2cd