Mycolactone toxin induces an inflammatory response by targeting the IL-1β pathway: Mechanistic insight into Buruli ulcer pathophysiology

Mycolactone, a lipid-like toxin, is the major virulence factor of Mycobacterium ulcerans, the etiological agent of Buruli ulcer. Its involvement in lesion development has been widely described in early stages of the disease, through its cytotoxic and immunosuppressive activities, but less is known a...

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Detalles Bibliográficos
Autores principales: Foulon, M., Robbe-Saule, M., Manry, J., Esnault, L., Boucaud, Y., Alcaïs, A., Malloci, M., Fanton d’Andon, M., Beauvais, T., Labarriere, N., Jeannin, P., Abel, L., Saint-André, J. P., Croué, A., Delneste, Y., Boneca, I. G., Marsollier, L., Marion, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748131/
https://www.ncbi.nlm.nih.gov/pubmed/33338061
http://dx.doi.org/10.1371/journal.ppat.1009107

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