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Asynchrony between virus diversity and antibody selection limits influenza virus evolution

Seasonal influenza viruses create a persistent global disease burden by evolving to escape immunity induced by prior infections and vaccinations. New antigenic variants have a substantial selective advantage at the population level, but these variants are rarely selected within-host, even in previou...

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Detalles Bibliográficos
Autores principales: Morris, Dylan H, Petrova, Velislava N, Rossine, Fernando W, Parker, Edyth, Grenfell, Bryan T, Neher, Richard A, Levin, Simon A, Russell, Colin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748417/
https://www.ncbi.nlm.nih.gov/pubmed/33174838
http://dx.doi.org/10.7554/eLife.62105