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Self-assembled particulate vaccine elicits strong immune responses and reduces Mycobacterium avium subsp. paratuberculosis infection in mice
Mycobacterium avium subspecies paratuberculosis (MAP) causes chronic progressive granulomatous enteritis leading to diarrhoea, weight loss, and eventual death in ruminants. Commercially available vaccines provide only partial protection against MAP infection and can compromise the use of bovine tube...
Autores principales: | Gupta, Sandeep K., Parlane, Natalie A., Luo, Dongwen, Rehm, Bernd H. A., Heiser, Axel, Buddle, Bryce M., Wedlock, D. Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749150/ https://www.ncbi.nlm.nih.gov/pubmed/33339863 http://dx.doi.org/10.1038/s41598-020-79407-7 |
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