Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase

RNA synthesis is central to life, and RNA polymerase (RNAP) depends on accessory factors for recovery from stalled states and adaptation to environmental changes. Here, we investigated the mechanism by which a helicase-like factor HelD recycles RNAP. We report a cryo-EM structure of a complex betwee...

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Detalles Bibliográficos
Autores principales: Kouba, Tomáš, Koval’, Tomáš, Sudzinová, Petra, Pospíšil, Jiří, Brezovská, Barbora, Hnilicová, Jarmila, Šanderová, Hana, Janoušková, Martina, Šiková, Michaela, Halada, Petr, Sýkora, Michal, Barvík, Ivan, Nováček, Jiří, Trundová, Mária, Dušková, Jarmila, Skálová, Tereza, Chon, URee, Murakami, Katsuhiko S., Dohnálek, Jan, Krásný, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749160/
https://www.ncbi.nlm.nih.gov/pubmed/33339823
http://dx.doi.org/10.1038/s41467-020-20158-4

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