Targeting presynaptic H3 heteroreceptor in nucleus accumbens to improve anxiety and obsessive-compulsive-like behaviors

Anxiety commonly co‐occurs with obsessive-compulsive disorder (OCD). Both of them are closely related to stress. However, the shared neurobiological substrates and therapeutic targets remain unclear. Here we report an amelioration of both anxiety and OCD via the histamine presynaptic H3 heterorecept...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Yang, Peng, Shi-Yu, Shen, Li-Ping, Zhuang, Qian-Xing, Li, Bin, Xie, Shu-Tao, Li, Qian-Xiao, Shi, Ming-Run, Ma, Tian-Yu, Zhang, Qipeng, Wang, Jian-Jun, Zhu, Jing-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749329/
https://www.ncbi.nlm.nih.gov/pubmed/33257584
http://dx.doi.org/10.1073/pnas.2008456117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749329/
https://www.ncbi.nlm.nih.gov/pubmed/33257584
http://dx.doi.org/10.1073/pnas.2008456117

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