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Targeting presynaptic H3 heteroreceptor in nucleus accumbens to improve anxiety and obsessive-compulsive-like behaviors
Anxiety commonly co‐occurs with obsessive-compulsive disorder (OCD). Both of them are closely related to stress. However, the shared neurobiological substrates and therapeutic targets remain unclear. Here we report an amelioration of both anxiety and OCD via the histamine presynaptic H3 heterorecept...
Autores principales: | Zhang, Xiao-Yang, Peng, Shi-Yu, Shen, Li-Ping, Zhuang, Qian-Xing, Li, Bin, Xie, Shu-Tao, Li, Qian-Xiao, Shi, Ming-Run, Ma, Tian-Yu, Zhang, Qipeng, Wang, Jian-Jun, Zhu, Jing-Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749329/ https://www.ncbi.nlm.nih.gov/pubmed/33257584 http://dx.doi.org/10.1073/pnas.2008456117 |
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