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Predictors of changes after reasoning training in healthy adults
OBJECTIVES: To investigate predictors of performance changes and their time course in healthy older adults. DESIGN: A post hoc analysis of a RCT investigating the effect of reasoning cognitive training (ReaCT) compared to an active control group (CG) during a time course. SETTING AND PARTICIPANTS: A...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749593/ https://www.ncbi.nlm.nih.gov/pubmed/32981211 http://dx.doi.org/10.1002/brb3.1861 |
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author | Roheger, Mandy Kalbe, Elke Corbett, Anne Brooker, Helen Ballard, Clive |
author_facet | Roheger, Mandy Kalbe, Elke Corbett, Anne Brooker, Helen Ballard, Clive |
author_sort | Roheger, Mandy |
collection | PubMed |
description | OBJECTIVES: To investigate predictors of performance changes and their time course in healthy older adults. DESIGN: A post hoc analysis of a RCT investigating the effect of reasoning cognitive training (ReaCT) compared to an active control group (CG) during a time course. SETTING AND PARTICIPANTS: An online, home‐based RCT including n = 4,310 healthy participants (ReaCT: n = 2,557; CG: n = 1,753) aged 50 years and older. METHODS: Multiple regression analyses were conducted to investigate predictors (age, sex, education, severity of depression, number of training sessions the participants attended, and neuropsychological baseline values) of the outcome measures grammatical reasoning, working memory, digit vigilance, verbal short‐term memory, and verbal learning at 6 weeks, 3, and 6 months. RESULTS: Being female and lower education predicted improvements in grammatical reasoning scores at 6 weeks and 3 months of training. CONCLUSION AND IMPLICATION: Identifying predictors for nonpharmacological interventions may help to set up a personalized medicine approach in order to prevent cognitive decline in healthy older adults. |
format | Online Article Text |
id | pubmed-7749593 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77495932020-12-23 Predictors of changes after reasoning training in healthy adults Roheger, Mandy Kalbe, Elke Corbett, Anne Brooker, Helen Ballard, Clive Brain Behav Original Research OBJECTIVES: To investigate predictors of performance changes and their time course in healthy older adults. DESIGN: A post hoc analysis of a RCT investigating the effect of reasoning cognitive training (ReaCT) compared to an active control group (CG) during a time course. SETTING AND PARTICIPANTS: An online, home‐based RCT including n = 4,310 healthy participants (ReaCT: n = 2,557; CG: n = 1,753) aged 50 years and older. METHODS: Multiple regression analyses were conducted to investigate predictors (age, sex, education, severity of depression, number of training sessions the participants attended, and neuropsychological baseline values) of the outcome measures grammatical reasoning, working memory, digit vigilance, verbal short‐term memory, and verbal learning at 6 weeks, 3, and 6 months. RESULTS: Being female and lower education predicted improvements in grammatical reasoning scores at 6 weeks and 3 months of training. CONCLUSION AND IMPLICATION: Identifying predictors for nonpharmacological interventions may help to set up a personalized medicine approach in order to prevent cognitive decline in healthy older adults. John Wiley and Sons Inc. 2020-09-27 /pmc/articles/PMC7749593/ /pubmed/32981211 http://dx.doi.org/10.1002/brb3.1861 Text en © 2020 The Authors. Brain and Behavior published by Wiley Periodicals LLC This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Roheger, Mandy Kalbe, Elke Corbett, Anne Brooker, Helen Ballard, Clive Predictors of changes after reasoning training in healthy adults |
title | Predictors of changes after reasoning training in healthy adults |
title_full | Predictors of changes after reasoning training in healthy adults |
title_fullStr | Predictors of changes after reasoning training in healthy adults |
title_full_unstemmed | Predictors of changes after reasoning training in healthy adults |
title_short | Predictors of changes after reasoning training in healthy adults |
title_sort | predictors of changes after reasoning training in healthy adults |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749593/ https://www.ncbi.nlm.nih.gov/pubmed/32981211 http://dx.doi.org/10.1002/brb3.1861 |
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