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A plausible involvement of plasmalemmal voltage‐dependent anion channel 1 in the neurotoxicity of 15‐deoxy‐Δ(12,14)‐prostaglandin J(2)

INTRODUCTION: 15‐deoxy‐Δ(12,14)‐prostaglandin J(2) (15d‐PGJ(2)) causes neuronal apoptosis independently of its nuclear receptor, peroxysome‐proliferator activated receptor γ. Its membrane receptor, chemoattractant receptor‐homologous molecule expressed on Th2 cells (CRTH2), did not also mediate the...

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Detalles Bibliográficos
Autores principales: Koma, Hiromi, Yamamoto, Yasuhiro, Okamura, Noboru, Yagami, Tatsurou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749624/
https://www.ncbi.nlm.nih.gov/pubmed/33200588
http://dx.doi.org/10.1002/brb3.1866