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The virtual circular genome model for primordial RNA replication

We propose a model for the replication of primordial protocell genomes that builds upon recent advances in the nonenzymatic copying of RNA. We suggest that the original genomes consisted of collections of oligonucleotides beginning and ending at all possible positions on both strands of one or more...

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Detalles Bibliográficos
Autores principales: Zhou, Lijun, Ding, Dian, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749632/
https://www.ncbi.nlm.nih.gov/pubmed/33028653
http://dx.doi.org/10.1261/rna.077693.120