Mutations in domain IV of elongation factor EF-G confer −1 frameshifting

A recent crystal structure of a ribosome complex undergoing partial translocation in the absence of elongation factor EF-G showed disruption of codon–anticodon pairing and slippage of the reading frame by −1, directly implicating EF-G in preservation of the translational reading frame. Among mutatio...

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Detalles Bibliográficos
Autores principales: Niblett, Dustin, Nelson, Charlotte, Leung, Calvin S., Rexroad, Gillian, Cozy, Jake, Zhou, Jie, Lancaster, Laura, Noller, Harry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749637/
https://www.ncbi.nlm.nih.gov/pubmed/33008838
http://dx.doi.org/10.1261/rna.077339.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749637/
https://www.ncbi.nlm.nih.gov/pubmed/33008838
http://dx.doi.org/10.1261/rna.077339.120

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