Cargando…

Coadministration of Ketamine and Perampanel Improves Behavioral Function and Reduces Inflammation in Acute Traumatic Brain Injury Mouse Model

Traumatic brain injury (TBI) is among the most debilitating neurological disorders with inadequate therapeutic options. It affects all age groups globally leading to post-TBI behavioral challenges and life-long disabilities requiring interventions for these health issues. In the current study, C57BL...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alqahtani, Faleh, Assiri, Mohammed A., Mohany, Mohamed, Imran, Imran, Javaid, Sana, Rasool, Muhammad Fawad, Shakeel, Waleed, Sivandzade, Farzane, Alanazi, Ahmed Z., Al-Rejaie, Salim S., Alshammari, Musaad A., Alasmari, Fawaz, Alanazi, Mohammed Mufadhe, Alamri, Faisal F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749776/ https://www.ncbi.nlm.nih.gov/pubmed/33381547 http://dx.doi.org/10.1155/2020/3193725

Ejemplares similares

Dynamics of Choline-Containing Phospholipids in Traumatic Brain Injury and Associated Comorbidities
por: Javaid, Sana, et al.
Publicado: (2021)

Non-pharmacological Interventions for Intractable Epilepsy
por: Alqahtani, Faleh, et al.
Publicado: (2020)

Vitamin D2 protects acute and repeated noise stress induced behavioral, biochemical, and histopathological alterations: Possible antioxidant effect
por: Samad, Noreen, et al.
Publicado: (2022)

Angiotensin II receptor Neprilysin inhibitor (LCZ696) compared to Valsartan attenuates Hepatotoxicity in STZ-induced hyperglycemic rats
por: Alqahtani, Faleh, et al.
Publicado: (2020)

Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats
por: Rehman, Zohabia, et al.
Publicado: (2022)

Neuroinflammatory Cytokines Induce Amyloid Beta Neurotoxicity through Modulating Amyloid Precursor Protein Levels/Metabolism
por: Alasmari, Fawaz, et al.
Publicado: (2018)

LCZ696 mitigates diabetic-induced nephropathy through inhibiting oxidative stress, NF-κB mediated inflammation and glomerulosclerosis in rats
por: Mohany, Mohamed, et al.
Publicado: (2020)

Nicotine and cotinine quantification after a 4-week inhalation of electronic cigarette vapors in male and female mice using UPLC-MS/MS
por: Alasmari, Fawaz, et al.
Publicado: (2022)

Development and Evaluation of Physiologically Based Pharmacokinetic Drug–Disease Models for Predicting Rifampicin Exposure in Tuberculosis and Cirrhosis Populations
por: Rasool, Muhammad F., et al.
Publicado: (2019)

Protective Role of Loranthus regularis against Liver Dysfunction, Inflammation, and Oxidative Stress in Streptozotocin Diabetic Rat Model
por: Alanazi, Ahmed Z., et al.
Publicado: (2020)

Physiologically Based Pharmacokinetic Model To Predict Metoprolol Disposition in Healthy and Disease Populations
por: Zamir, Ammara, et al.
Publicado: (2023)

Traumatic Brain Injury and Blood–Brain Barrier (BBB): Underlying Pathophysiological Mechanisms and the Influence of Cigarette Smoking as a Premorbid Condition
por: Sivandzade, Farzane, et al.
Publicado: (2020)

Impact of chronic smoking on traumatic brain microvascular injury: An in vitro study
por: Sivandzade, Farzane, et al.
Publicado: (2021)

Effects of Chronic Inhalation of Electronic Cigarette Vapor Containing Nicotine on Neurobehaviors and Pre/Postsynaptic Neuron Markers
por: Alasmari, Fawaz, et al.
Publicado: (2022)

Protective effect of diosmin against doxorubicin-induced nephrotoxicity
por: Ali, Nemat, et al.
Publicado: (2021)

Geraniol Ameliorates Doxorubicin-Mediated Kidney Injury through Alteration of Antioxidant Status, Inflammation, and Apoptosis: Potential Roles of NF-κB and Nrf2/Ho-1
por: AlAsmari, Abdullah F., et al.
Publicado: (2022)

Neuroinflammation and Its Impact on the Pathogenesis of COVID-19
por: Almutairi, Mohammed M., et al.
Publicado: (2021)

Liraglutide attenuates gefitinib-induced cardiotoxicity and promotes cardioprotection through the regulation of MAPK/NF-κB signaling pathways
por: AlAsmari, Abdullah F., et al.
Publicado: (2020)

Renin angiotensin system blockage by losartan neutralize hypercholesterolemia-induced inflammatory and oxidative injuries
por: AlSaad, Abdulaziz M.S., et al.
Publicado: (2020)

Chemical Profiling and Dose-Dependent Assessment of Fear Reducing and Memory-Enhancing Effects of Solanum virginianum in Rats
por: Javaid, Usman, et al.
Publicado: (2021)

The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study
por: Sivandzade, Farzane, et al.
Publicado: (2020)

Amelioration of Scopolamine-Induced Amnesic, Anxiolytic and Antidepressant Effects of Ficus benghalensis in Behavioral Experimental Models
por: Malik, Humna, et al.
Publicado: (2020)

Chemical characterization and evaluation of the neuroprotective potential of Indigofera sessiliflora through in-silico studies and behavioral tests in scopolamine-induced memory compromised rats
por: Sajjad Haider, Muhammad, et al.
Publicado: (2021)

Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting Haloperidol Exposure in Healthy and Disease Populations
por: Alasmari, Mohammed S., et al.
Publicado: (2022)

Grewia asiatica Berry Juice Diminishes Anxiety, Depression, and Scopolamine-Induced Learning and Memory Impairment in Behavioral Experimental Animal Models
por: Imran, Imran, et al.
Publicado: (2021)

Elucidation of the Molecular Mechanisms Underlying Sorafenib-Induced Hepatotoxicity
por: AlAsmari, Abdullah F., et al.
Publicado: (2020)

Application of a physiologically based pharmacokinetic model in predicting captopril disposition in children with chronic kidney disease
por: Khalid, Sundus, et al.
Publicado: (2023)

Pharmacological Modulation of Smooth Muscles and Platelet Aggregation by Psidium cattleyanum
por: Rahman, Hafiz Muhammad Abdur, et al.
Publicado: (2020)

Antidiabetic Drugs Can Reduce the Harmful Impact of Chronic Smoking on Post-Traumatic Brain Injuries
por: Sivandzade, Farzane, et al.
Publicado: (2023)

Long-Term Supplementation of Syzygium cumini (L.) Skeels Concentrate Alleviates Age-Related Cognitive Deficit and Oxidative Damage: A Comparative Study of Young vs. Old Mice
por: Malik, Nosheen, et al.
Publicado: (2023)

Supplementation of Morin Restores the Altered Bone Histomorphometry in Hyperglycemic Rodents via Regulation of Insulin/IGF-1 Signaling
por: Abuohashish, Hatem M., et al.
Publicado: (2021)

Development and evaluation of physiologically based pharmacokinetic drug-disease models for predicting captopril pharmacokinetics in chronic diseases
por: Rasool, Muhammad F., et al.
Publicado: (2021)

Chronically administered Agave americana var. marginata extract ameliorates diabetes mellitus, associated behavioral comorbidities and biochemical parameters in alloxan-induced diabetic rats
por: Aleem, Ambreen, et al.
Publicado: (2022)

Demographics, comorbidities, and outcomes among young and middle-aged COVID-19 patients in Saudi Arabia
por: Alali, Amer S., et al.
Publicado: (2021)

Physiologically-based pharmacokinetic modeling for single and multiple dosing regimens of ceftriaxone in healthy and chronic kidney disease populations: a tool for model-informed precision dosing
por: Alasmari, Fawaz, et al.
Publicado: (2023)

Ketamine–Propofol Coadministration for Induction and Infusion Maintenance in Anesthetized Dogs: Effects on Electroencephalography and Antinociception
por: Ko, Jeff C., et al.
Publicado: (2023)

Development and Evaluation of a Physiologically Based Pharmacokinetic Drug-Disease Model of Propranolol for Suggesting Model Informed Dosing in Liver Cirrhosis Patients
por: Kalam, Muhammad Nasir, et al.
Publicado: (2021)

A Cross-Sectional Study to Evaluate Antimicrobial Susceptibility of Uropathogens from South Punjab, Pakistan
por: Idrees, Muhammad Mubashar, et al.
Publicado: (2022)

Assessing the protective effect of rosiglitazone against electronic cigarette/tobacco smoke-induced blood–brain barrier impairment
por: Sivandzade, Farzane, et al.
Publicado: (2019)

Anti-Diabetic Countermeasures Against Tobacco Smoke-Dependent Cerebrovascular Toxicity: Use and Effect of Rosiglitazone
por: Sivandzade, Farzane, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b60sbeeb3n32u669hnefri0bpk