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Extracellular vesicles released by adipose tissue-derived mesenchymal stromal/stem cells from obese pigs fail to repair the injured kidney

AIMS: Mesenchymal stromal/stem cell (MSC)-derived extracellular vesicles (EVs) shuttle select MSC contents and are endowed with an ability to repair ischemic tissues. We hypothesized that exposure to cardiovascular risk factors may alter the microRNA cargo of MSC-derived EVs, blunting their capacity...

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Detalles Bibliográficos
Autores principales:	Eirin, Alfonso, Ferguson, Christopher M., Zhu, Xiang-Yang, Saadiq, Ishran M., Tang, Hui, Lerman, Amir, Lerman, Lilach O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749840/ https://www.ncbi.nlm.nih.gov/pubmed/32592955 http://dx.doi.org/10.1016/j.scr.2020.101877

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