Cargando…

Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria

BACKGROUND: Sex specific differences appear particularly relevant in the management of type 2 DM. OBJECTIVE: We determined gender specific differences in cardio-metabolic risk, microvascular and macrovascular complications in patients with type 2 diabetes. METHODS: Four hundred type 2 diabetes patie...

Descripción completa

Detalles Bibliográficos
Autores principales: Enikuomehin, Adenike, Kolawole, Babatope A, Soyoye, Olubukunmi D, Adebayo, Joseph O, Ikem, Rosemary T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750067/
https://www.ncbi.nlm.nih.gov/pubmed/33402918
http://dx.doi.org/10.4314/ahs.v20i1.35
_version_ 1783625416593899520
author Enikuomehin, Adenike
Kolawole, Babatope A
Soyoye, Olubukunmi D
Adebayo, Joseph O
Ikem, Rosemary T
author_facet Enikuomehin, Adenike
Kolawole, Babatope A
Soyoye, Olubukunmi D
Adebayo, Joseph O
Ikem, Rosemary T
author_sort Enikuomehin, Adenike
collection PubMed
description BACKGROUND: Sex specific differences appear particularly relevant in the management of type 2 DM. OBJECTIVE: We determined gender specific differences in cardio-metabolic risk, microvascular and macrovascular complications in patients with type 2 diabetes. METHODS: Four hundred type 2 diabetes patients, males and females, matched for age and disease duration were recruited from the diabetes clinic. Relevant clinical and laboratory information were obtained or performed. RESULTS: 190(47.5%) were male and 210 (52.5%) were female respectively. The mean age of the study population was 60.6 + 9.93 years. Women had higher prevalence of hypertension (and obesity. Mean total cholesterol was significantly higher in women but men were more likely to achieve LDL treatment goals than women (69.5% vs 59.0%, p<0.05). More women (47.1% & 31.4%) reached glycaemic goals of <10mmol/l for 2HPP and HBA1c of <7.0%. There were no gender differences in the distribution of microvascular and macrovascular complications (p>0.05) but women were more likely to develop moderate and severe diabetic retinopathy (p= 0.027). CONCLUSION: Women with T2DM had worse cardiometabolic risk profile with regards to hypertension, obesity and lipid goals. Men achieved therapeutic goals less frequently than did women in terms of glycaemia. Microvascular and macrovascular complications occurred commonly in both sexes.
format Online
Article
Text
id pubmed-7750067
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Makerere Medical School
record_format MEDLINE/PubMed
spelling pubmed-77500672021-01-04 Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria Enikuomehin, Adenike Kolawole, Babatope A Soyoye, Olubukunmi D Adebayo, Joseph O Ikem, Rosemary T Afr Health Sci Articles BACKGROUND: Sex specific differences appear particularly relevant in the management of type 2 DM. OBJECTIVE: We determined gender specific differences in cardio-metabolic risk, microvascular and macrovascular complications in patients with type 2 diabetes. METHODS: Four hundred type 2 diabetes patients, males and females, matched for age and disease duration were recruited from the diabetes clinic. Relevant clinical and laboratory information were obtained or performed. RESULTS: 190(47.5%) were male and 210 (52.5%) were female respectively. The mean age of the study population was 60.6 + 9.93 years. Women had higher prevalence of hypertension (and obesity. Mean total cholesterol was significantly higher in women but men were more likely to achieve LDL treatment goals than women (69.5% vs 59.0%, p<0.05). More women (47.1% & 31.4%) reached glycaemic goals of <10mmol/l for 2HPP and HBA1c of <7.0%. There were no gender differences in the distribution of microvascular and macrovascular complications (p>0.05) but women were more likely to develop moderate and severe diabetic retinopathy (p= 0.027). CONCLUSION: Women with T2DM had worse cardiometabolic risk profile with regards to hypertension, obesity and lipid goals. Men achieved therapeutic goals less frequently than did women in terms of glycaemia. Microvascular and macrovascular complications occurred commonly in both sexes. Makerere Medical School 2020-03 /pmc/articles/PMC7750067/ /pubmed/33402918 http://dx.doi.org/10.4314/ahs.v20i1.35 Text en © 2020 Enikuomehin A et al. Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Enikuomehin, Adenike
Kolawole, Babatope A
Soyoye, Olubukunmi D
Adebayo, Joseph O
Ikem, Rosemary T
Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria
title Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria
title_full Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria
title_fullStr Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria
title_full_unstemmed Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria
title_short Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria
title_sort influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, ile-ife, nigeria
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750067/
https://www.ncbi.nlm.nih.gov/pubmed/33402918
http://dx.doi.org/10.4314/ahs.v20i1.35
work_keys_str_mv AT enikuomehinadenike influenceofgenderonthedistributionoftype2diabeticcomplicationsattheobafemiawolowoteachinghospitalileifenigeria
AT kolawolebabatopea influenceofgenderonthedistributionoftype2diabeticcomplicationsattheobafemiawolowoteachinghospitalileifenigeria
AT soyoyeolubukunmid influenceofgenderonthedistributionoftype2diabeticcomplicationsattheobafemiawolowoteachinghospitalileifenigeria
AT adebayojosepho influenceofgenderonthedistributionoftype2diabeticcomplicationsattheobafemiawolowoteachinghospitalileifenigeria
AT ikemrosemaryt influenceofgenderonthedistributionoftype2diabeticcomplicationsattheobafemiawolowoteachinghospitalileifenigeria