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2D Zernike polynomial expansion: Finding the protein-protein binding regions

We present a method for efficiently and effectively assessing whether and where two proteins can interact with each other to form a complex. This is still largely an open problem, even for those relatively few cases where the 3D structure of both proteins is known. In fact, even if much of the infor...

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Detalles Bibliográficos
Autores principales: Milanetti, Edoardo, Miotto, Mattia, Di Rienzo, Lorenzo, Monti, Michele, Gosti, Giorgio, Ruocco, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750141/
https://www.ncbi.nlm.nih.gov/pubmed/33363707
http://dx.doi.org/10.1016/j.csbj.2020.11.051