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Glycocalyx sialic acids regulate Nrf2-mediated signaling by fluid shear stress in human endothelial cells

Activation of the nuclear factor erythroid 2–related factor 2 (Nrf2) pathway is critical for vascular endothelial redox homeostasis in regions of high, unidirectional shear stress (USS), however the underlying mechanosensitive mediators are not fully understood. The endothelial glycocalyx is disrupt...

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Detalles Bibliográficos
Autores principales: Psefteli, Paraskevi-Maria, Kitscha, Phoebe, Vizcay, Gema, Fleck, Roland, Chapple, Sarah J., Mann, Giovanni E., Fowler, Mark, Siow, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750408/
https://www.ncbi.nlm.nih.gov/pubmed/33340902
http://dx.doi.org/10.1016/j.redox.2020.101816