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Glycocalyx sialic acids regulate Nrf2-mediated signaling by fluid shear stress in human endothelial cells
Activation of the nuclear factor erythroid 2–related factor 2 (Nrf2) pathway is critical for vascular endothelial redox homeostasis in regions of high, unidirectional shear stress (USS), however the underlying mechanosensitive mediators are not fully understood. The endothelial glycocalyx is disrupt...
Autores principales: | Psefteli, Paraskevi-Maria, Kitscha, Phoebe, Vizcay, Gema, Fleck, Roland, Chapple, Sarah J., Mann, Giovanni E., Fowler, Mark, Siow, Richard C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750408/ https://www.ncbi.nlm.nih.gov/pubmed/33340902 http://dx.doi.org/10.1016/j.redox.2020.101816 |
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