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Addition of TLR9 agonist immunotherapy to radiation improves systemic antitumor activity
Radiotherapy (RT) has been used to control tumors by physically damaging DNA and inducing apoptosis; it also promotes antitumor immune responses via neoantigens release and augmenting immune-oncology agents to elicit systemic response. Tumor regression after RT can recruit inflammatory cells, such a...
Autores principales: | Younes, Ahmed I., Barsoumian, Hampartsoum B., Sezen, Duygu, Verma, Vivek, Patel, Roshal, Wasley, Mark, Hu, Yun, Dunn, Joe D., He, Kewen, Chen, Dawei, Menon, Hari, Masrorpour, Fatemeh, Gu, Meidi, Yang, Liangpeng, Puebla-Osorio, Nahum, Cortez, Maria Angelica, Welsh, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750418/ https://www.ncbi.nlm.nih.gov/pubmed/33340886 http://dx.doi.org/10.1016/j.tranon.2020.100983 |
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