Cargando…

Discovery of Novel Biosynthetic Gene Cluster Diversity From a Soil Metagenomic Library

Soil microorganisms historically have been a rich resource for natural product discovery, yet the majority of these microbes remain uncultivated and their biosynthetic capacity is left underexplored. To identify the biosynthetic potential of soil microorganisms using a culture-independent approach,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santana-Pereira, Alinne L. R., Sandoval-Powers, Megan, Monsma, Scott, Zhou, Jinglie, Santos, Scott R., Mead, David A., Liles, Mark R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750434/ https://www.ncbi.nlm.nih.gov/pubmed/33365020 http://dx.doi.org/10.3389/fmicb.2020.585398

Ejemplares similares

Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery
por: Xu, Peng, et al.
Publicado: (2020)

Influence of soil nutrients on the presence and distribution of CPR bacteria in a long-term crop rotation experiment
por: Santana-Pereira, Alinne L. R., et al.
Publicado: (2023)

A rapid and efficient strategy to identify and recover biosynthetic gene clusters from soil metagenomes
por: Negri, Timo, et al.
Publicado: (2022)

Insights into rumen microbial biosynthetic gene cluster diversity through genome-resolved metagenomics
por: Anderson, Christopher L., et al.
Publicado: (2021)

Insights into novel antimicrobial compounds and antibiotic resistance genes from soil metagenomes
por: de Castro, Alinne P., et al.
Publicado: (2014)

Novel archaeal thermostable cellulases from an oil reservoir metagenome
por: Lewin, Anna, et al.
Publicado: (2017)

Secondary metabolite biosynthetic diversity in Arctic Ocean metagenomes
por: Rego, Adriana, et al.
Publicado: (2021)

TOUCAN: a framework for fungal biosynthetic gene cluster discovery
por: Almeida, Hayda, et al.
Publicado: (2020)

Recovery and functional validation of hidden soil enzymes in metagenomic libraries
por: Calderon, Dayana, et al.
Publicado: (2019)

Discovery of the Pseudomonas Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity
por: Mullins, Alex J., et al.
Publicado: (2021)

Mining metagenomes reveals diverse antibiotic biosynthetic genes in uncultured microbial communities
por: Amin, Dina H., et al.
Publicado: (2023)

Dispersant Effects on Single-Walled Carbon Nanotube Antibacterial Activity
por: Noor, Matthew M., et al.
Publicado: (2022)

Discovery of Pyranoviolin A and Its Biosynthetic Gene Cluster in Aspergillus violaceofuscus
por: Wei, Xingxing, et al.
Publicado: (2020)

Discovery of an Abundance of Biosynthetic Gene Clusters in Shark Bay Microbial Mats
por: Chen, Ray, et al.
Publicado: (2020)

Expression of fungal biosynthetic gene clusters in S. cerevisiae for natural product discovery
por: Liu, Zihe, et al.
Publicado: (2021)

Biosynthetic potential of uncultured Antarctic soil bacteria revealed through long-read metagenomic sequencing
por: Waschulin, Valentin, et al.
Publicado: (2021)

iPRESTO: Automated discovery of biosynthetic sub-clusters linked to specific natural product substructures
por: Louwen, Joris J. R., et al.
Publicado: (2023)

Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in the fungus Glarea lozoyensis
por: Chen, Li, et al.
Publicado: (2013)

Discovery and characterization of a Gram-positive Pel polysaccharide biosynthetic gene cluster
por: Whitfield, Gregory B., et al.
Publicado: (2020)

Biosynthetic Interrogation of Soil Metagenomes Reveals Metamarin, an Uncommon Cyclomarin Congener with Activity against Mycobacterium tuberculosis
por: Li, Lei, et al.
Publicado: (2021)

Evolution and Diversity of Biosynthetic Gene Clusters in Fusarium
por: Hoogendoorn, Koen, et al.
Publicado: (2018)

Open resource metagenomics: a model for sharing metagenomic libraries
por: Neufeld, J.D., et al.
Publicado: (2011)

Mining Novel Constitutive Promoter Elements in Soil Metagenomic Libraries in Escherichia coli
por: Westmann, Cauã A., et al.
Publicado: (2018)

Large-Scale Metagenome Assembly Reveals Novel Animal-Associated Microbial Genomes, Biosynthetic Gene Clusters, and Other Genetic Diversity
por: Youngblut, Nicholas D., et al.
Publicado: (2020)

Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery
por: Bourne, Christina R.
Publicado: (2014)

A heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters: discovery of the Aspergillus fumigatus sartorypyrone biosynthetic pathway
por: Lin, Shu-Yi, et al.
Publicado: (2023)

Heterologous expression of Avermectins biosynthetic gene cluster by construction of a Bacterial Artificial Chromosome library of the producers
por: Deng, Qian, et al.
Publicado: (2017)

Complete genome of Staphylococcus aureus Tager 104 provides evidence of its relation to modern systemic hospital-acquired strains
por: Davis, Richard W., et al.
Publicado: (2016)

A Genomics Based Discovery of Secondary Metabolite Biosynthetic Gene Clusters in Aspergillus ustus
por: Pi, Borui, et al.
Publicado: (2015)

Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species
por: Wang, Xue, et al.
Publicado: (2018)

Recent Advances in Strategies for Activation and Discovery/Characterization of Cryptic Biosynthetic Gene Clusters in Streptomyces
por: Nguyen, Chung Thanh, et al.
Publicado: (2020)

A widely distributed genus of soil Acidobacteria genomically enriched in biosynthetic gene clusters
por: Crits-Christoph, Alexander, et al.
Publicado: (2022)

Discovery of Novel Antibiotic Resistance Determinants in Forest and Grassland Soil Metagenomes
por: Willms, Inka Marie, et al.
Publicado: (2019)

Discovery and characterizaton of a novel lipase with transesterification activity from hot spring metagenomic library
por: Yan, Wei, et al.
Publicado: (2016)

Expression of heterologous sigma factors enables functional screening of metagenomic and heterologous genomic libraries
por: Gaida, Stefan M., et al.
Publicado: (2015)

Discovery of Unusual Biaryl Polyketides by Activation of a Silent Streptomyces venezuelae Biosynthetic Gene Cluster
por: Thanapipatsiri, Anyarat, et al.
Publicado: (2016)

Discovery, Bioactivity Evaluation, Biosynthetic Gene Cluster Identification, and Heterologous Expression of Novel Albofungin Derivatives
por: She, Weiyi, et al.
Publicado: (2021)

Identification of Novel Rotihibin Analogues in Streptomyces scabies, Including Discovery of Its Biosynthetic Gene Cluster
por: Planckaert, Sören, et al.
Publicado: (2021)

Discovery and overproduction of novel highly bioactive pamamycins through transcriptional engineering of the biosynthetic gene cluster
por: Eckert, Nikolas, et al.
Publicado: (2023)

BiosyntheticSPAdes: reconstructing biosynthetic gene clusters from assembly graphs
por: Meleshko, Dmitry, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rb63itdi41nluogi32bq1qvkgj