Cargando…

Chondrocyte ferroptosis contribute to the progression of osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a complex process comprised of mechanical load, inflammation, and metabolic factors. It is still unknown that if chondrocytes undergo ferroptosis during OA and if ferroptosis contribute to the progression of OA. MATERIALS AND METHODS: In our study, we use Interleuk...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Xudong, Sun, Kai, Yu, Shengnan, Luo, Jiahui, Guo, Jiachao, Lin, Jiamin, Wang, Genchun, Guo, Zhou, Ye, Yaping, Guo, Fengjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chinese Speaking Orthopaedic Society 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750492/ https://www.ncbi.nlm.nih.gov/pubmed/33376672 http://dx.doi.org/10.1016/j.jot.2020.09.006

Ejemplares similares

Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
por: Guo, Zhou, et al.
Publicado: (2022)

Corrigendum: Deferoxamine alleviates osteoarthritis by inhibiting chondrocyte ferroptosis and activating the Nrf2 pathway
por: Guo, Zhou, et al.
Publicado: (2023)

Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis
por: Sun, Kai, et al.
Publicado: (2019)

PKM2 suppresses osteogenesis and facilitates adipogenesis by regulating β-catenin signaling and mitochondrial fusion and fission
por: Guo, Jiachao, et al.
Publicado: (2020)

Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis
por: Zhang, Xiong, et al.
Publicado: (2023)

PERK controls bone homeostasis through the regulation of osteoclast differentiation and function
por: Guo, Jiachao, et al.
Publicado: (2020)

Growth differentiation factor 5 in cartilage and osteoarthritis: A possible therapeutic candidate
por: Sun, Kai, et al.
Publicado: (2021)

PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway
por: Yao, Xudong, et al.
Publicado: (2020)

Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis
por: Hou, Liangcai, et al.
Publicado: (2023)

Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy
por: Sun, Kai, et al.
Publicado: (2023)

Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways
por: Yao, Xudong, et al.
Publicado: (2019)

Mitophagy in degenerative joint diseases
por: Sun, Kai, et al.
Publicado: (2020)

miR-1 Inhibits the Ferroptosis of Chondrocyte by Targeting CX43 and Alleviates Osteoarthritis Progression
por: Zhou, Ming, et al.
Publicado: (2023)

D‐mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF‐2α‐dependent manner
por: Zhou, Xueman, et al.
Publicado: (2021)

SCD1 deficiency exacerbates osteoarthritis by inducing ferroptosis in chondrocytes
por: Yu, Chao, et al.
Publicado: (2023)

Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
por: Miao, Yu, et al.
Publicado: (2022)

Increased 15-lipoxygenase-1 expression in chondrocytes contributes to the pathogenesis of osteoarthritis
por: Chen, Kaizhe, et al.
Publicado: (2017)

PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis
por: Xue, Xiang, et al.
Publicado: (2023)

Specificity protein 1-mediated ACSL4 transcription promoted the osteoarthritis progression through suppressing the ferroptosis of chondrocytes
por: He, Wen, et al.
Publicado: (2023)

Recent Insights into the Contribution of the Changing Hypertrophic Chondrocyte Phenotype in the Development and Progression of Osteoarthritis
por: Ripmeester, Ellen G. J., et al.
Publicado: (2018)

Basic fibroblast growth factor increases IFT88 expression in chondrocytes
por: Zhan, Daolu, et al.
Publicado: (2017)

Identification of EGFR as an essential regulator in chondrocytes ferroptosis of osteoarthritis using bioinformatics, in vivo, and in vitro study
por: Sun, Hong, et al.
Publicado: (2023)

Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subchondral osteosclerosis and angiogenesis
por: Yan, Jiangbo, et al.
Publicado: (2022)

Crosstalk between ferroptosis and chondrocytes in osteoarthritis: a systematic review of in vivo and in vitro studies
por: Cao, Siyang, et al.
Publicado: (2023)

The Role of Autophagy in Chondrocyte Metabolism and Osteoarthritis: A Comprehensive Research Review
por: Luo, Pan, et al.
Publicado: (2019)

Osteopontin (OPN) alleviates the progression of osteoarthritis by promoting the anabolism of chondrocytes
por: Luo, Wei, et al.
Publicado: (2022)

Anti-chondrocyte apoptosis effect of genistein in treating inflammation-induced osteoarthritis
por: Zou, Yang, et al.
Publicado: (2020)

The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression
por: Rim, Yeri Alice, et al.
Publicado: (2020)

Sirt6 attenuates chondrocyte senescence and osteoarthritis progression
por: Ji, Ming-liang, et al.
Publicado: (2022)

Targeting miR-18a sensitizes chondrocytes to anticytokine therapy to prevent osteoarthritis progression
por: Lian, Chengjie, et al.
Publicado: (2020)

BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice
por: Shao, Yan, et al.
Publicado: (2021)

Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice
por: Li, Zhen, et al.
Publicado: (2023)

Role of IFT88 in icariin-regulated maintenance of the chondrocyte phenotype
por: Xiang, Wei, et al.
Publicado: (2018)

Targeting Cell Death: Pyroptosis, Ferroptosis, Apoptosis and Necroptosis in Osteoarthritis
por: Yang, Jian, et al.
Publicado: (2022)

Role of Chondrocytes in Cartilage Formation, Progression of Osteoarthritis and Cartilage Regeneration
por: Akkiraju, Hemanth, et al.
Publicado: (2015)

Pravastatin Reduces Matrix Metalloproteinases Expression and Promotes Cholesterol Efflux in Osteoarthritis Chondrocytes
por: Wu, Yunpeng, et al.
Publicado: (2022)

Aquaporin 1 contributes to chondrocyte apoptosis in a rat model of osteoarthritis
por: Gao, Hangfei, et al.
Publicado: (2016)

Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis
por: Shin, Hyo Jung, et al.
Publicado: (2019)

Anti-Dlx5 Retards the Progression of Osteoarthritis through Inhibiting Chondrocyte Hypertrophy and Apoptosis
por: Lu, Ye, et al.
Publicado: (2022)

Abnormal expression of miR-4784 in chondrocytes of osteoarthritis and associations with chondrocyte hyperplasia
por: Liu, Jing, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_qd3kpnkd29pe1j9099doh0ean4