Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

To compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). Sensitivity was 94% for nasopharyngeal and 75% for midturbinate swabs (P = .0001). In 88 nasop...

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Detalles Bibliográficos
Autores principales: Jamal, Alainna J., Mozafarihashjin, Mohammad, Coomes, Eric, Anceva-Sami, Sofia, Barati, Shiva, Crowl, Gloria, Faheem, Amna, Farooqi, Lubna, Kandel, Christopher E., Khan, Saman, Li, Angel X., Mistry, Henna, Paterson, Aimee, Plenderleith, Simon, Prost, Karren, Poutanen, Susan, Powis, Jeff, Schryer, Renée, Taylor, Maureen, Yip, Lily, Zhong, Xi Zoe, McGeer, Allison J., Mubareka, Samira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Concise Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750656/
https://www.ncbi.nlm.nih.gov/pubmed/33203496
http://dx.doi.org/10.1017/ice.2020.1326
Descripción
Sumario:To compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). Sensitivity was 94% for nasopharyngeal and 75% for midturbinate swabs (P = .0001). In 88 nasopharyngeal/midturbinate pairs with matched saliva, sensitivity was 86% for nasopharyngeal swabs and 88% for combined midturbinate swabs/saliva.

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