Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

To compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). Sensitivity was 94% for nasopharyngeal and 75% for midturbinate swabs (P = .0001). In 88 nasop...

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Autores principales: Jamal, Alainna J., Mozafarihashjin, Mohammad, Coomes, Eric, Anceva-Sami, Sofia, Barati, Shiva, Crowl, Gloria, Faheem, Amna, Farooqi, Lubna, Kandel, Christopher E., Khan, Saman, Li, Angel X., Mistry, Henna, Paterson, Aimee, Plenderleith, Simon, Prost, Karren, Poutanen, Susan, Powis, Jeff, Schryer, Renée, Taylor, Maureen, Yip, Lily, Zhong, Xi Zoe, McGeer, Allison J., Mubareka, Samira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Concise Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750656/
https://www.ncbi.nlm.nih.gov/pubmed/33203496
http://dx.doi.org/10.1017/ice.2020.1326
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author Jamal, Alainna J.
Mozafarihashjin, Mohammad
Coomes, Eric
Anceva-Sami, Sofia
Barati, Shiva
Crowl, Gloria
Faheem, Amna
Farooqi, Lubna
Kandel, Christopher E.
Khan, Saman
Li, Angel X.
Mistry, Henna
Paterson, Aimee
Plenderleith, Simon
Prost, Karren
Poutanen, Susan
Powis, Jeff
Schryer, Renée
Taylor, Maureen
Yip, Lily
Zhong, Xi Zoe
McGeer, Allison J.
Mubareka, Samira
author_facet Jamal, Alainna J.
Mozafarihashjin, Mohammad
Coomes, Eric
Anceva-Sami, Sofia
Barati, Shiva
Crowl, Gloria
Faheem, Amna
Farooqi, Lubna
Kandel, Christopher E.
Khan, Saman
Li, Angel X.
Mistry, Henna
Paterson, Aimee
Plenderleith, Simon
Prost, Karren
Poutanen, Susan
Powis, Jeff
Schryer, Renée
Taylor, Maureen
Yip, Lily
Zhong, Xi Zoe
McGeer, Allison J.
Mubareka, Samira
author_sort Jamal, Alainna J.
collection PubMed
description To compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). Sensitivity was 94% for nasopharyngeal and 75% for midturbinate swabs (P = .0001). In 88 nasopharyngeal/midturbinate pairs with matched saliva, sensitivity was 86% for nasopharyngeal swabs and 88% for combined midturbinate swabs/saliva.
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spelling pubmed-77506562020-12-21 Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Jamal, Alainna J. Mozafarihashjin, Mohammad Coomes, Eric Anceva-Sami, Sofia Barati, Shiva Crowl, Gloria Faheem, Amna Farooqi, Lubna Kandel, Christopher E. Khan, Saman Li, Angel X. Mistry, Henna Paterson, Aimee Plenderleith, Simon Prost, Karren Poutanen, Susan Powis, Jeff Schryer, Renée Taylor, Maureen Yip, Lily Zhong, Xi Zoe McGeer, Allison J. Mubareka, Samira Infect Control Hosp Epidemiol Concise Communication To compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). Sensitivity was 94% for nasopharyngeal and 75% for midturbinate swabs (P = .0001). In 88 nasopharyngeal/midturbinate pairs with matched saliva, sensitivity was 86% for nasopharyngeal swabs and 88% for combined midturbinate swabs/saliva. Cambridge University Press 2020-11-18 /pmc/articles/PMC7750656/ /pubmed/33203496 http://dx.doi.org/10.1017/ice.2020.1326 Text en © The Society for Healthcare Epidemiology of America 2020 http://creativecommons.org/licenses/by/4.0/ This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Concise Communication
Jamal, Alainna J.
Mozafarihashjin, Mohammad
Coomes, Eric
Anceva-Sami, Sofia
Barati, Shiva
Crowl, Gloria
Faheem, Amna
Farooqi, Lubna
Kandel, Christopher E.
Khan, Saman
Li, Angel X.
Mistry, Henna
Paterson, Aimee
Plenderleith, Simon
Prost, Karren
Poutanen, Susan
Powis, Jeff
Schryer, Renée
Taylor, Maureen
Yip, Lily
Zhong, Xi Zoe
McGeer, Allison J.
Mubareka, Samira
Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
title Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
title_full Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
title_fullStr Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
title_full_unstemmed Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
title_short Sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
title_sort sensitivity of midturbinate versus nasopharyngeal swabs for the detection of severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
topic Concise Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750656/
https://www.ncbi.nlm.nih.gov/pubmed/33203496
http://dx.doi.org/10.1017/ice.2020.1326
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