Early preclinical screening using zebrafish (Danio rerio) reveals the safety of the candidate anti-inflammatory therapeutic agent TnP

The patented anti-inflammatory peptide TnP had its effectiveness recently confirmed in vivo in a murine model of multiple sclerosis and asthma. In this work, the safety of the TnP was evaluated in investigative toxicology tests using zebrafish (Danio rerio) as a model. We conducted the OECD #236 tes...

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Detalles Bibliográficos
Autores principales: Batista-Filho, João, Falcão, Maria Alice Pimentel, Maleski, Adolfo Luis Almeida, Soares, Amanda Beatriz Silva, Balan-Lima, Leticia, Disner, Geonildo Rodrigo, Lima, Carla, Lopes-Ferreira, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750688/
https://www.ncbi.nlm.nih.gov/pubmed/33364179
http://dx.doi.org/10.1016/j.toxrep.2020.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750688/
https://www.ncbi.nlm.nih.gov/pubmed/33364179
http://dx.doi.org/10.1016/j.toxrep.2020.12.004

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