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Early preclinical screening using zebrafish (Danio rerio) reveals the safety of the candidate anti-inflammatory therapeutic agent TnP
The patented anti-inflammatory peptide TnP had its effectiveness recently confirmed in vivo in a murine model of multiple sclerosis and asthma. In this work, the safety of the TnP was evaluated in investigative toxicology tests using zebrafish (Danio rerio) as a model. We conducted the OECD #236 tes...
Autores principales: | Batista-Filho, João, Falcão, Maria Alice Pimentel, Maleski, Adolfo Luis Almeida, Soares, Amanda Beatriz Silva, Balan-Lima, Leticia, Disner, Geonildo Rodrigo, Lima, Carla, Lopes-Ferreira, Monica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750688/ https://www.ncbi.nlm.nih.gov/pubmed/33364179 http://dx.doi.org/10.1016/j.toxrep.2020.12.004 |
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