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Recent trends on wound management: New therapeutic choices based on polymeric carriers

Wound healing is an unmet therapeutic challenge among medical society since wound assessment and management is a complex procedure including several factors playing major role in healing process. Wounds can mainly be categorized as acute or chronic. It is well referred that the acute wound displays...

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Autores principales: Okur, Mehmet Evren, Karantas, Ioannis D., Şenyiğit, Zeynep, Üstündağ Okur, Neslihan, Siafaka, Panoraia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750807/
https://www.ncbi.nlm.nih.gov/pubmed/33363624
http://dx.doi.org/10.1016/j.ajps.2019.11.008
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author Okur, Mehmet Evren
Karantas, Ioannis D.
Şenyiğit, Zeynep
Üstündağ Okur, Neslihan
Siafaka, Panoraia I.
author_facet Okur, Mehmet Evren
Karantas, Ioannis D.
Şenyiğit, Zeynep
Üstündağ Okur, Neslihan
Siafaka, Panoraia I.
author_sort Okur, Mehmet Evren
collection PubMed
description Wound healing is an unmet therapeutic challenge among medical society since wound assessment and management is a complex procedure including several factors playing major role in healing process. Wounds can mainly be categorized as acute or chronic. It is well referred that the acute wound displays normal wound physiology while healing, in most cases, is seemed to progress through the normal phases of wound healing. On the other hand, a chronic wound is physiologically impaired. The main problem in wound management is that the majority of wounds are colonized with microbes, whereas this does not mean that all wounds will be infected. In this review, we address the problems that clinicians face to manage while treat acute and chronic wounds. Moreover, we demonstrate the pathophysiology, etiology, prognosis and microbiology of wounds. We further introduce the state of art in pharmaceutical technology field as part of wound management aiming to assist health professionals to overcome the current implications on wound assessment. In addition, authors review researches which included the use of gels and dermal films as wound healing agents. It can be said that natural and synthetic drugs or carriers provide promising solutions in order to meet the wound management standards. However, are the current strategies as desirable as medical society wish?
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spelling pubmed-77508072020-12-23 Recent trends on wound management: New therapeutic choices based on polymeric carriers Okur, Mehmet Evren Karantas, Ioannis D. Şenyiğit, Zeynep Üstündağ Okur, Neslihan Siafaka, Panoraia I. Asian J Pharm Sci Review Wound healing is an unmet therapeutic challenge among medical society since wound assessment and management is a complex procedure including several factors playing major role in healing process. Wounds can mainly be categorized as acute or chronic. It is well referred that the acute wound displays normal wound physiology while healing, in most cases, is seemed to progress through the normal phases of wound healing. On the other hand, a chronic wound is physiologically impaired. The main problem in wound management is that the majority of wounds are colonized with microbes, whereas this does not mean that all wounds will be infected. In this review, we address the problems that clinicians face to manage while treat acute and chronic wounds. Moreover, we demonstrate the pathophysiology, etiology, prognosis and microbiology of wounds. We further introduce the state of art in pharmaceutical technology field as part of wound management aiming to assist health professionals to overcome the current implications on wound assessment. In addition, authors review researches which included the use of gels and dermal films as wound healing agents. It can be said that natural and synthetic drugs or carriers provide promising solutions in order to meet the wound management standards. However, are the current strategies as desirable as medical society wish? Shenyang Pharmaceutical University 2020-11 2020-01-23 /pmc/articles/PMC7750807/ /pubmed/33363624 http://dx.doi.org/10.1016/j.ajps.2019.11.008 Text en © 2020 Shenyang Pharmaceutical University. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Okur, Mehmet Evren
Karantas, Ioannis D.
Şenyiğit, Zeynep
Üstündağ Okur, Neslihan
Siafaka, Panoraia I.
Recent trends on wound management: New therapeutic choices based on polymeric carriers
title Recent trends on wound management: New therapeutic choices based on polymeric carriers
title_full Recent trends on wound management: New therapeutic choices based on polymeric carriers
title_fullStr Recent trends on wound management: New therapeutic choices based on polymeric carriers
title_full_unstemmed Recent trends on wound management: New therapeutic choices based on polymeric carriers
title_short Recent trends on wound management: New therapeutic choices based on polymeric carriers
title_sort recent trends on wound management: new therapeutic choices based on polymeric carriers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750807/
https://www.ncbi.nlm.nih.gov/pubmed/33363624
http://dx.doi.org/10.1016/j.ajps.2019.11.008
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