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Genetic risk for Alzheimer’s disease influences neuropathology via multiple biological pathways

Alzheimer’s disease is a highly heritable, common neurodegenerative disease characterized neuropathologically by the accumulation of β-amyloid plaques and tau-containing neurofibrillary tangles. In addition to the well-established risk associated with the APOE locus, there has been considerable succ...

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Detalles Bibliográficos
Autores principales: Hannon, Eilis, Shireby, Gemma L, Brookes, Keeley, Attems, Johannes, Sims, Rebecca, Cairns, Nigel J, Love, Seth, Thomas, Alan J, Morgan, Kevin, Francis, Paul T, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750986/
https://www.ncbi.nlm.nih.gov/pubmed/33376986
http://dx.doi.org/10.1093/braincomms/fcaa167