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Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a prevalent articular disorder and has no entirely satisfactory treatment. Punicalagin (PUG) is a polyphenol which has shown multiple pharmacological effects on various diseases. However, the role of PUG in the treatment of OA has not been well defined. METHODS: Th...

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Detalles Bibliográficos
Autores principales:	Kong, Jinsong, Wang, Jiacheng, Gong, Xiaokang, Zheng, Xin, Chen, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751323/ https://www.ncbi.nlm.nih.gov/pubmed/33364748 http://dx.doi.org/10.2147/DDDT.S282932

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