Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells

Mitochondrial anti-apoptotic Bcl2 and BclxL proteins, are overexpressed in multiple tumour types, and has been involved in the progression and survival of malignant cells. Therefore, inhibition of such proteins has become a validated and attractive target for anticancer drug discovery. In this manne...

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Detalles Bibliográficos
Autores principales: Eldehna, Wagdy M., Abo-Ashour, Mahmoud F., Al-Warhi, Tarfah, Al-Rashood, Sara T., Alharbi, Amal, Ayyad, Rezk R., Al-Khayal, Khayal, Abdulla, Maha, Abdel-Aziz, Hatem A., Ahmad, Rehan, El-Haggar, Radwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751403/
https://www.ncbi.nlm.nih.gov/pubmed/33345633
http://dx.doi.org/10.1080/14756366.2020.1862100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751403/
https://www.ncbi.nlm.nih.gov/pubmed/33345633
http://dx.doi.org/10.1080/14756366.2020.1862100

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