Cargando…
Novel positive allosteric modulators of A(2B) adenosine receptor acting as bone mineralisation promoters
Small-molecules acting as positive allosteric modulators (PAMs) of the A(2B) adenosine receptor (A(2B) AR) could potentially represent a novel therapeutic strategy for pathological conditions characterised by altered bone homeostasis, including osteoporosis. We investigated a library of compounds (4...
Autores principales: | Barresi, Elisabetta, Giacomelli, Chiara, Marchetti, Laura, Baglini, Emma, Salerno, Silvia, Greco, Giovanni, Da Settimo, Federico, Martini, Claudia, Trincavelli, Maria Letizia, Taliani, Sabrina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751416/ https://www.ncbi.nlm.nih.gov/pubmed/33334192 http://dx.doi.org/10.1080/14756366.2020.1862103 |
Ejemplares similares
-
Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A(2B) AR Physio-Pathological Implications
por: Barresi, Elisabetta, et al.
Publicado: (2021) -
Carbonic Anhydrase Activators for Neurodegeneration: An Overview
por: Poggetti, Valeria, et al.
Publicado: (2022) -
The Alpha Keto
Amide Moiety as a Privileged Motif
in Medicinal Chemistry: Current Insights and Emerging Opportunities
por: Robello, Marco, et al.
Publicado: (2021) -
Dual Targeting Topoisomerase/G-Quadruplex Agents in Cancer Therapy—An Overview
por: Salerno, Silvia, et al.
Publicado: (2022) -
Target-Based Anticancer Indole Derivatives for the Development of Anti-Glioblastoma Agents
por: Salerno, Silvia, et al.
Publicado: (2023)