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Arecoline suppresses epithelial cell viability by upregulating tropomyosin-1 through the transforming growth factor-β/Smad pathway

CONTEXT: Oral submucous fibrosis (OSF) is a chronic and progressive disease. Arecoline, present in betel nuts, has been proposed as a vital aetiological factor. However, the underlying mechanism remains unclear. OBJECTIVES: This research elucidates the expression of tropomyosin-1 (TPM1) and its regu...

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Detalles Bibliográficos
Autores principales:	Li, Long, Gu, Liqun, Yao, Zhigang, Wang, Yuehong, Tang, Zhangui, Wu, Xiaoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751430/ https://www.ncbi.nlm.nih.gov/pubmed/33332205 http://dx.doi.org/10.1080/13880209.2020.1851729

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