Atezolizumab alleviates the immunosuppression induced by PD-L1-positive neutrophils and improves the survival of mice during sepsis

Atezolizumab can reduce immunosuppression caused by T lymphocyte apoptosis in various cancer types. The current study aimed to investigate whether this drug can also alleviate immunosuppression during sepsis. For that purpose, a C57BL/6 mouse sepsis model was generated. Mice were randomly assigned t...

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Detalles Bibliográficos
Autores principales: Chen, Jianxin, Chen, Ruiyuan, Huang, Shaoxiong, Zu, Bin, Zhang, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751480/
https://www.ncbi.nlm.nih.gov/pubmed/33655320
http://dx.doi.org/10.3892/mmr.2020.11783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751480/
https://www.ncbi.nlm.nih.gov/pubmed/33655320
http://dx.doi.org/10.3892/mmr.2020.11783

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