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Prevalence of HIV-1 Integrase Strand Transfer Inhibitor Resistance in Treatment-Naïve Voluntary Counselling and Testing Clients by Population Sequencing and Illumina Next-Generation Sequencing in Taiwan

PURPOSE: Integrase strand transfer inhibitors (INSTIs) are used as first-line therapy for HIV-1-infected patients. Next-generation sequencing (NGS) can detect low-frequency mutants; however, the clinical value of NGS to detect resistance variants is unknown. This study aimed to evaluate the prevalen...

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Detalles Bibliográficos
Autores principales:	Tsai, Hung-Chin, Chen, I-Tzu, Tsai, Kuo-Wang, Lee, Susan Shin-Jung, Chen, Yao-Shen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751586/ https://www.ncbi.nlm.nih.gov/pubmed/33364799 http://dx.doi.org/10.2147/IDR.S273704

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