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Downregulation of IRAK1 Prevents the Malignant Behavior of Hepatocellular Carcinoma Cells by Blocking Activation of the MAPKs/NLRP3/IL-1β Pathway

INTRODUCTION: Interleukin-1 receptor-associated kinase 1 (IRAK1) was shown to contribute to a variety of cancer-related processes. However, the function of IRAK1 in hepatocellular carcinoma (HCC) pathogenesis has not been investigated in detail. METHODS: IRAK1 expression in HCC was examined by immun...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Wei, Tao, Chen, Yinghua, Yang, Lan, Wu, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751837/
https://www.ncbi.nlm.nih.gov/pubmed/33363384
http://dx.doi.org/10.2147/OTT.S260793