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Downregulation of IRAK1 Prevents the Malignant Behavior of Hepatocellular Carcinoma Cells by Blocking Activation of the MAPKs/NLRP3/IL-1β Pathway

INTRODUCTION: Interleukin-1 receptor-associated kinase 1 (IRAK1) was shown to contribute to a variety of cancer-related processes. However, the function of IRAK1 in hepatocellular carcinoma (HCC) pathogenesis has not been investigated in detail. METHODS: IRAK1 expression in HCC was examined by immun...

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Detalles Bibliográficos
Autores principales:	Chen, Wei, Wei, Tao, Chen, Yinghua, Yang, Lan, Wu, Xiaomin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751837/ https://www.ncbi.nlm.nih.gov/pubmed/33363384 http://dx.doi.org/10.2147/OTT.S260793

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