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The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins

SARS Coronavirus 2 (SARS-CoV-2) emerged in late 2019, leading to the Coronavirus Disease 2019 (COVID-19) pandemic that continues to cause significant global mortality in human populations. Given its sequence similarity to SARS-CoV, as well as related coronaviruses circulating in bats, SARS-CoV-2 is...

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Detalles Bibliográficos
Autores principales: Conceicao, Carina, Thakur, Nazia, Human, Stacey, Kelly, James T., Logan, Leanne, Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Zagrajek, Adrian K., Hollinghurst, Philippa, Varga, Michal, Tsirigoti, Christina, Tully, Matthew, Chiu, Chris, Moffat, Katy, Silesian, Adrian Paul, Hammond, John A., Maier, Helena J., Bickerton, Erica, Shelton, Holly, Dietrich, Isabelle, Graham, Stephen C., Bailey, Dalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751883/
https://www.ncbi.nlm.nih.gov/pubmed/33347434
http://dx.doi.org/10.1371/journal.pbio.3001016

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